3-MeO-PCE

What is 3-MeO-PCE?

3-Methoxyeticyclidine, better known as 3-MeO-PCE, is an emerging research compound that is gaining interest among Dutch consumers interested in psychoactive substances. In this overview, we delve deeper into its chemical properties, effects on the human body, and relevant regulations.

Product specifications

• Chemical name: 3-Methoxyeticyclidine (3-MeO-PCE)
• IUPAC name: N-Ethyl-1-(3-methoxyphenyl)cyclohexan-1-amine
• Molecular formula: C15H23NO
• Molecular mass: 233.355 g/mol
• CAS number: 1364933-80-1
• SMILES: CCNC1(CCCCC1)C2=CC(=CC=C2)OC
• InChI: InChI=1S/C15H23NO/c1-3-16-15(10-5-4-6-11-15)13-8-7-9-14(12-13)17-2/h7-9,12,16H,3-6,10-11H2,1-2H3

Regulations in Europe

• Germany: NpSG (For industrial and scientific purposes only)
• United Kingdom: Class B
• Sweden and Switzerland: Illegal

Effects on the human body

3-MeO-PCE falls into the category of dissociative anesthetics, similar to PCE and PCP. It acts primarily on the NMDA receptor and has a strong affinity for the PCP binding site, which contributes to its psychoactive effects.

• Receptor binding:
  • NMDA receptor: Ki value of 61 nM
  • Dopamine transporter: Ki value of 743 nM
  • Serotonin transporter: Ki value of 115 nM
  • Histamine H2 receptor: Ki value of 2097 nM
  • Alpha-2A-adrenergic receptor: Ki value of 964 nM
  • Sigma receptors (σ1 and σ2): Ki values ​​of 4519 nM and 525 nM respectively

Potential effects

As a dissociative anesthetic, 3-MeO-PCE can cause altered sensory perception, hallucinations, and a sense of disconnection from both the environment and the self. It is known for its psychoactive properties and potential to induce psychotic disorders.

Market information

The target group for 3-MeO-PCE consists of Dutch consumers interested in research drugs and psychoactive substances. Due to the restricted status of this drug, specific documents may be required for purchase and use. It is crucial to follow local regulations for sale and distribution.